文獻：肽-PEG-脂質復合物的合成方法：奧曲肽-PEG-DSPE合成的應用

鏈接：https://www.sciencedirect.com/science/article/abs/pii/S0960894X08007944

作者：蘇建秋  ，曾錦 祿 ，張定光  ，余文仁  ，吳世光 

節選：

建立了一種肽-聚乙二醇-脂質（肽-PEG-脂質）偶聯物的固相合成方法。以奧曲肽-PEG 2000 -DSPE（OPD 2000）為例，演示了該合成方法。所得OPD 2000的結構、活性和純度均已確認，為制備靶向脂質體等結構明確的藥物遞送系統提供了靶向分子，以供進一步研究。

A solid phase synthesis method was established for the synthesis of peptide-poly(ethylene glycol)-lipid (peptide-PEG-lipid) conjugates. Octreotide-PEG2000-DSPE (OPD2000) was used as an example to demonstrate the synthetic approach. The OPD2000 obtained had confirmed structure, activity, and purity providing a targeting molecule for preparation of well-defined drug delivery systems, such as targeted liposomes, for further studies.

西安齊岳生物提供相關產品：

DSPE-PEG-Boronate

mPEG-DMPE

EB1-PEG-DSPE

DSPE-PEG-HZ

DSPE-PEG-PEI

DSPE-PEG-c(RGDfc)

DMPE (14:0 PE)

DSPE-PEG-scFv(HD37-CCH)（二硬脂酰基磷脂酰乙醇胺-聚乙二醇-腫瘤靶向蛋白)

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