新型磁共振成像納米膠束型磁共振造影劑的技術

核磁共振是一種**的非侵入性臨床診斷技術，但是受限于其靈敏度，針對**組織與正常組織微環境間的差異，特別是微小溫度差異的檢測并不能取得很好的效果。

發展了一種對生理溫度范圍內微小溫度差異進行檢測的新方法。研究者制備了一種納米膠束型磁共振造影劑增強其靈敏度，該種造影劑能在人體生理溫度范圍內對微小的溫度變化做出響應。利用熱敏型膠束作為載體，研究者們設計了這種基于化學交換飽和轉移成像的納米磁共振造影劑。這種直徑小于100納米的膠束粒子在37度發生結構和形態的變化，改變了造影劑所攜帶結合水所在微環境的化學交換速率，進而使得其化學交換飽和轉移效應發生了明顯的改變。通過化學交換飽和轉移成像方法，研究者們獲得這種溫度敏感型造影劑對不同溫度時信號的智能放大。由于響應的溫度范圍接近人體生理溫度，使得該造影劑在臨床應用上具有重要意義。

產品供應：

影像對比劑

活體熒光造影劑

Sulfo-CY7(Cyanine7) NHSester活體熒光造影劑

Sulfo-CY7-NHS,Sulfo-Cyanine7.5NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

sulfo-CY7(Cyanine7) maleimide活體熒光造影劑

sulfo-CY7-MAL,sulfo-Cyanine7.5maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) dicarboxylicacid活體熒光造影劑

Sulfo-Cyanine7.5dicarboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) carboxylicacid活體熒光造影劑

Sulfo-Cy7COOHSulfo-Cyanine7.5carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) azide活體熒光造影劑

Sulfo-CY7/N3,Sulfo-Cyanine7.5azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) alkyne活體熒光造影劑

Sulfo-CY7-alkyne,Sulfo-Cyanine7.5alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) tetrazine活體熒光造影劑

Sulfo-Cyanine7tetrazine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) NHSester活體熒光造影劑

Sulfo-Cyanine7NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) maleimide活體熒光造影劑

Sulfo-Cyanine7maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

sulfo-CY7(Cyanine7) dicarboxylicacid活體熒光造影劑

sulfo-Cyanine7dicarboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) carboxylicacid活體熒光造影劑

Sulfo-Cyanine7carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) bis-NHSester活體熒光造影劑

Sulfo-Cyanine7bis-NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) azide活體熒光造影劑

Sulfo-Cyanine7azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) amine活體熒光造影劑

Sulfo-Cyanine7amine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

Sulfo-CY7(Cyanine7) alkyne活體熒光造影劑

Sulfo-Cyanine7alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) tetrazine活體熒光造影劑

Cyanine7.5tetrazine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) NHSester活體熒光造影劑

Cyanine7.5NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) maleimide活體熒光造影劑

Cyanine7.5maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) hydrazide活體熒光造影劑

Cyanine7.5hydrazide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) carboxylicacid活體熒光造影劑

Cyanine7.5carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7 (Cyanine7) azide活體熒光造影劑

Cyanine7.5azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7 (Cyanine7) azide,10mM/DMSO活體熒光造影劑

Cyanine7.5azide,10mM/DMSO,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) amine活體熒光造影劑

Cyanine7.5amine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) alkyne活體熒光造影劑

Cyanine7.5alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) tetrazine活體熒光造影劑

Cyanine7tetrazine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) NHSester活體熒光造影劑

Cyanine7NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) maleimide活體熒光造影劑

Cyanine7maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) hydrazide活體熒光造影劑

Cyanine7hydrazide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) dicarboxylicacid活體熒光造影劑

Cyanine7dicarboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) DBCO活體熒光造影劑

Cyanine7DBCO,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) carboxylicacid活體熒光造影劑

Cyanine7carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) azide活體熒光造影劑

Cyanine7azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) azide,10mM/DMSO活體熒光造影劑

Cyanine7azide,10mM/DMSO,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) amine活體熒光造影劑

Cyanine7amine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

CY7(Cyanine7) alkyne活體熒光造影劑

Cyanine7alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

BDP650/665XNHSester活體熒光造影劑

BDP650/665XNHSester,Borondipyrromethenedyeforfluorescein(516nm)channel-verybrightandphotostablefluorophore.

BDP650/665maleimide活體熒光造影劑

BDP650/665maleimide,Borondipyrromethenedyeforfluorescein(515nm)channel-verybrightandphotostablefluorophore.

BDP650/665azide活體熒光造影劑

BDP650/665azide,Borondipyrromethenedyeforfluorescein(514nm)channel-verybrightandphotostablefluorophore.

BDP650/665alkyne活體熒光造影劑

BDP650/665alkyne,Borondipyrromethenedyeforfluorescein(513nm)channel-verybrightandphotostablefluorophore.

BDP630/650XNHSester活體熒光造影劑

BDP630/650XNHSester,Borondipyrromethenedyeforfluorescein(512nm)channel-verybrightandphotostablefluorophore.

BDP630/650tetrazine活體熒光造影劑

BDP630/650tetrazine,Borondipyrromethenedyeforfluorescein(511nm)channel-verybrightandphotostablefluorophore.

BDP630/650maleimide活體熒光造影劑

BDP630/650maleimide,Borondipyrromethenedyeforfluorescein(510nm)channel-verybrightandphotostablefluorophore.

BDP630/650hydrazide活體熒光造影劑

BDP630/650hydrazide,Borondipyrromethenedyeforfluorescein(509nm)channel-verybrightandphotostablefluorophore.

BDP630/650carboxylicacid活體熒光造影劑

BDP630/650carboxylicacid,Borondipyrromethenedyeforfluorescein(508nm)channel-verybrightandphotostablefluorophore.

BDP630/650azide活體熒光造影劑

BDP630/650azide,Borondipyrromethenedyeforfluorescein(507nm)channel-verybrightandphotostablefluorophore.

BDP630/650amine活體熒光造影劑

BDP630/650amine,Borondipyrromethenedyeforfluorescein(506nm)channel-verybrightandphotostablefluorophore.

BDP630/650alkyne活體熒光造影劑

BDP630/650alkyne,Borondipyrromethenedyeforfluorescein(505nm)channel-verybrightandphotostablefluorophore.

T2型造影劑-超順磁性四氧化三鐵顆粒（USPIO/SPIO）

T2對比劑（順磁性鐵錳）

普魯士藍納米顆粒

普魯士藍納米顆粒；純水溶液；粒徑：100nm

親和素表面磁性氧化鐵微球（1um）

1um親和素包裹的磁性四氧化三鐵微球；純水溶液；粒徑：1±0.1um

羧基表面磁性氧化鐵微球（1um）

1um羧基化磁微球；純水溶液；粒徑：1±0.1um

磁性氧化鐵納米球（500nm）

500nm磁性氧化鐵納米球；純水溶液；粒徑：300±50nm

磁性氧化鐵納米球（300nm）

300nm磁性氧化鐵納米球；純水溶液；粒徑：300±50nm

磁性氧化鐵納米球（200nm）

200nm磁性氧化鐵納米球；純水溶液；粒徑：200±50nm

PEG化磁性錳鋅鐵氧體納米晶（氨基）

PEG化磁性錳鋅鐵氧體納米晶（-NH2）；純水溶液；粒徑：10±5nm

PEG化磁性錳鋅鐵氧體納米晶（羧基）

PEG化磁性錳鋅鐵氧體納米晶（-COOH）；純水溶液；粒徑：10±5nm

PEG化磁性錳鋅鐵氧體納米晶（甲氧基）

PEG化磁性錳鋅鐵氧體納米晶（-OCH3）；純水溶液；粒徑：10±5nm

錳鋅鐵氧體納米晶

錳鋅鐵氧體納米晶（高溫熱解法）；氯仿溶液；粒徑：25±5nm

熒光素標記Fe3O4顆粒;USPIO;SA-DSPE-PEG-Fe3O4

熒光素修飾的四氧化三鐵磁性納米顆粒（FITC-Fe3O4）；純水溶液；粒徑：10±5nm

親和素表面Fe3O4顆粒SA-DSPE-PEG-Fe3O4;10nm

鏈霉親和素修飾的四氧化三鐵磁性納米顆粒（SA-Fe3O4）；純水溶液；粒徑：10±5nm

氨基端PEG化Fe3O4顆粒;DSPE-PEG-Fe3O4（-NH2）;10nm

PEG化四氧化三鐵磁性納米顆粒（-NH2）；純水溶液；粒徑：10±5nm

羧基端PEG化Fe3O4顆粒;DSPE-PEG-Fe3O4（-COOH）;10nm

PEG化四氧化三鐵磁性納米顆粒（-COOH）；純水溶液；粒徑：10±5nm

甲氧基PEG化Fe3O4顆粒;DSPE-PEG-Fe3O4（-CH3O）；50nm

PEG化四氧化三鐵磁性納米顆粒（-OCH3）；氯仿溶液；粒徑：50±5nm

PEG化Fe3O4顆粒;25nm;PEG-Fe3O4

PEG化四氧化三鐵磁性納米顆粒（-OCH3）；純水溶液；粒徑：25±5nm

PEG化Fe3O4顆粒;PEG-USPIO；10nm

PEG化四氧化三鐵磁性納米顆粒（-OCH3）；純水溶液；粒徑：10±5nm

油酸表面Fe3O4顆粒氯仿溶液;OA-Fe3O4-C

油酸修飾的四氧化三鐵磁性納米顆粒（OA-Fe3O4，高溫熱解法）；氯仿溶液；粒徑：10±5nm

油酸表面Fe3O4顆粒粉末;OA-USPIO

油酸修飾的四氧化三鐵磁性納米顆粒（OA-Fe3O4，高溫熱解法）；固體粉末；粒徑：10±5nm

磁性石墨烯;MagneticGR

磁性石墨烯溶液（500mg）

載USPIO聚苯乙烯納米粒

磁性聚苯乙烯納米球（PS-Fe3O4）；純水溶液；粒徑：100±50nm

二氧化硅表面Fe3O4顆粒;SiO2-Fe3O4

二氧化硅修飾的四氧化三鐵磁性納米顆粒（SiO2-Fe3O4）；純水溶液；粒徑：10±5nm

羧基表面Fe3O4顆粒;DMSA-USPIO

羧基化四氧化三鐵磁性納米顆粒（DMSA-Fe3O4）；純水溶液；粒徑：10±5nm

PEI氨基表面Fe3O4顆粒;PEI-USPIO

聚乙烯亞胺修飾的四氧化三鐵磁性納米顆粒（PEI-Fe3O4）；純水溶液；粒徑：10±5nm

油酸表面Fe3O4顆粒;OA-USPIO

油酸修飾的四氧化三鐵磁性納米顆粒（OA-Fe3O4，共沉淀法）；純水溶液；粒徑：10±5nm

氨基表面Fe2O3顆粒；APTS-Fe2O3

氨基化三氧化二鐵磁性納米顆粒（APTS-Fe2O3）；純水溶液；粒徑：10±5nm

羧基表面Fe2O3顆粒；DMSA-Fe2O3

羧基化三氧化二鐵磁性納米顆粒（DMSA-Fe2O3)；純水溶液；粒徑：10±5nm

PLL修飾Fe2O3顆粒

PLL-Fe2O3多聚賴氨酸修飾的三氧化二鐵磁性納米顆粒（PLL-Fe2O3）；純水溶液；粒徑：10±5nm

γ-Fe2O3

伽馬-三氧化二鐵磁性納米顆粒（γ-Fe2O3）；純水溶液；粒徑：10±5nm

上述產品齊岳生物均可供應，僅用于科研！

wyf 04.05